Tranexamic acid in bilateral total knee replacement
نویسندگان
چکیده
منابع مشابه
Topical usage of Tranexamic Acid: Comparative Analysis in Patients with Bilateral Total Knee Replacement
Aim: Topical Tranexamic acid (TXA) application provides maximum concentration of TXA at the bleeding site and avoids potential systemic effects. A number of blinded randomized control trials (RCT) have been published proving its safety and effectiveness. We hypothesised that in a person undergoing total knee replacement, if TXA was used topically on one side, it would reduce blood loss compared...
متن کاملTranexamic Acid and Total Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most commonly performed elective orthopaedic procedures in the United States [1]. By 2030, the number is estimated to grow by 673% to 3.48 million TKAs performed a year [1]. TKA provides significant pain relief and improvement in quality of life [2]. However TKA surgery is not without complications. Of note is the risk of bleeding and requirement for ...
متن کاملThe effectiveness and safety of tranexamic acid in bilateral total knee arthroplasty
OBJECTIVE A meta-analysis was performed to investigate the effectiveness and safety of tranexamic acid (TXA) for the treatment of blood loss after a bilateral total knee arthroplasty (TKA). METHODS Patients prepared for bilateral TKA and intervention including TXA versus placebo were comprehensively retrieved from MEDLINE (PubMed), Embase, Cochrane Central Register of Controlled Trials (CENTR...
متن کاملTopical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
BACKGROUND To examine the safety and efficacy of topical use of tranexamic acid (TA) in total knee arthroplasty (TKA). METHODS An electronic literature search of PubMed Medline; Ovid Medline; Embase; and the Cochrane Library was performed, identifying studies published in any language from 1966 to February 2013. The studies enrolled adults undergoing a primary TKA, where topical TA was used. ...
متن کاملTranexamic acid in total knee replacement: a systematic review and meta-analysis.
We conducted a systematic review and meta-analysis of randomised controlled trials evaluating the effect of tranexamic acid (TXA) upon blood loss and transfusion in primary total knee replacement. The review used the generic evaluation tool designed by the Cochrane Bone, Joint and Muscle Trauma Group. A total of 19 trials were eligible: 18 used intravenous administration, one also evaluated ora...
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ژورنال
عنوان ژورنال: Indian Journal of Orthopaedics
سال: 2011
ISSN: 0019-5413
DOI: 10.4103/0019-5413.87138